Description

1-(2-Bromo-3-Fluorophenyl)Propan-1-One is a high-purity fluorinated aromatic ketone building block of significant importance in advanced organic synthesis. Its unique structure, featuring both bromo and fluoro substituents, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where the fluorine atom enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for liquid crystals, organic semiconductors, and other functional polymers requiring halogenated aromatic cores.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Negishi, or Stille couplings for carbon-carbon bond formation.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Details
Product Name	1-(2-Bromo-3-Fluorophenyl)Propan-1-One
CAS No.	1261775-92-1
Molecular Formula	C9H8BrFO
Molecular Weight	231.06 g/mol
Synonyms	2-Bromo-3-fluoropropiophenone; 1-Propanone, 1-(2-bromo-3-fluorophenyl)-; 3'-Fluoro-2'-bromopropiophenone; α-Bromo-3-fluoropropiophenone (ambiguous, verify structure); 2-Bromo-3-fluorophenyl ethyl ketone; (2-Bromo-3-fluorophenyl)propan-1-one; 1-(2-Bromo-3-fluorophenyl)propan-1-one
EINECS	Contact for details

Quality Control

Every batch of 1-(2-Bromo-3-Fluorophenyl)Propan-1-One is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.