Description

1H-Pyrrolo[3,2-B]Pyridine-5-Carboxaldehyde is a high-value heterocyclic building block and key synthetic intermediate. This compound matters for its crucial role in constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and advanced materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry and organic synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing novel chemical libraries in drug discovery programs for oncology, CNS, and anti-inflammatory targets.
• Agrochemical Development: Employed in the research and synthesis of new crop protection agents and herbicides.
• Organic Synthesis Building Block: Acts as a key starting material for the preparation of more complex fused heterocyclic systems and functionalized derivatives.
• Material Science Research: Investigated as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic semiconductors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	1H-Pyrrolo[3,2-B]Pyridine-5-Carboxaldehyde
CAS No.	1261730-68-0
Molecular Formula	C8H6N2O
Molecular Weight	146.15 g/mol
Synonyms	5-Formyl-1H-pyrrolo[3,2-b]pyridine; 1H-Pyrrolo[3,2-b]pyridine-5-carbaldehyde; 5-Aldehydo-1H-pyrrolo[3,2-b]pyridine; 5-Pyrrolo[3,2-b]pyridinecarboxaldehyde; 1H-Pyrrolo[3,2-b]pyridine-5-carboxaldehyde; 5-Carbaldehyde-1H-pyrrolo[3,2-b]pyridine; Pyrrolo[3,2-b]pyridine-5-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[3,2-B]Pyridine-5-Carboxaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation and light, prolonged exposure to air or light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.