Description

2-Chloro-5-Iodo-Benzylchloride is a versatile halogenated benzyl chloride derivative that serves as a critical building block in advanced organic synthesis. Its unique bifunctional structure, featuring both chloro and iodo substituents, enables selective and sequential cross-coupling reactions, making it invaluable for constructing complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring halogenated aromatic scaffolds.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the iodine atom facilitates further functionalization.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the creation of organic electronic materials, liquid crystals, and advanced polymers.
• Cross-Coupling Reactions: The reactive benzyl chloride and aryl iodide groups make it an excellent substrate for Suzuki, Sonogashira, and Buchwald-Hartwig amination reactions.
• Custom Chemical Synthesis: A valuable reagent for contract research organizations (CROs) and fine chemical manufacturers producing bespoke compounds for clients.

Basic Information

Product Name	2-Chloro-5-Iodo-Benzylchloride
CAS No.	1261671-12-8
Molecular Formula	C7H5Cl2I
Molecular Weight	302.93 g/mol
Synonyms	1-(Chloromethyl)-2-chloro-5-iodobenzene; 2-Chloro-5-iodobenzyl Chloride; (2-Chloro-5-iodophenyl)methyl Chloride; α,2-Dichloro-5-iodotoluene; Benzene, 1-(chloromethyl)-2-chloro-5-iodo-; 5-Iodo-2-chlorobenzyl Chloride
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Iodo-Benzylchloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. Due to the light-sensitive and reactive nature of the compound, containers should be kept sealed under an inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.