Description

3,4-Dichloro-5-Trifluoromethylacetophenone is a high-value, multi-functional aromatic ketone building block. This compound is essential for its role as a key intermediate in the synthesis of complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and crop protection industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-inflammatory pathways.
• Agrochemical Synthesis: Serves as a key building block for developing advanced herbicides and fungicides with enhanced efficacy and selectivity.
• Material Science Research: Used in the development of specialty polymers and advanced organic materials due to its unique trifluoromethyl and halogenated structure.
• Ligand and Catalyst Development: Employed in organic chemistry research for creating novel ligands and catalysts used in cross-coupling and other catalytic reactions.
• Fluorine Chemistry Studies: Acts as a valuable substrate for investigating the effects of fluorine substitution on molecular properties and reactivity.

Basic Information

Product Name	3,4-Dichloro-5-Trifluoromethylacetophenone
CAS No.	1261645-17-3
Molecular Formula	C9H5Cl2F3O
Molecular Weight	257.04 g/mol
Synonyms	1-(3,4-Dichloro-5-(trifluoromethyl)phenyl)ethan-1-one; 3',4'-Dichloro-5'-(trifluoromethyl)acetophenone; 3,4-Dichloro-α,α,α-trifluoro-5-acetyltoluene; 3,4-Dichloro-5-(trifluoromethyl)acetophenone; 1-[3,4-Dichloro-5-(trifluoromethyl)phenyl]ethanone; Acetophenone, 3,4-dichloro-5-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 3,4-Dichloro-5-Trifluoromethylacetophenone is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.