Description

1-(4-Bromo-3-Chlorophenyl)Propan-1-One is a high-purity, halogenated aromatic ketone building block of significant importance in advanced organic synthesis. Its precise molecular structure makes it a critical intermediate for the development of complex active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel molecular frameworks.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and anti-inflammatory agents.
• Agrochemical Synthesis: Serves as a crucial precursor in the development of next-generation herbicides and fungicides, leveraging its halogenated phenyl group.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Material Science Research: Employed as a monomer or building block for synthesizing specialty polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1-(4-Bromo-3-Chlorophenyl)Propan-1-One
CAS No.	1261583-09-8
Molecular Formula	C9H8BrClO
Molecular Weight	247.52 g/mol
Synonyms	1-Propanone, 1-(4-bromo-3-chlorophenyl)-; 4'-Bromo-3'-chloropropiophenone; 3-Chloro-4-bromopropiophenone; 1-(4-Bromo-3-chlorophenyl)propan-1-one; 4-Bromo-3-chloropropiophenone; p-Bromo-m-chloropropiophenone; (4-Bromo-3-chlorophenyl) ethyl ketone
EINECS	Contact for details

Quality Control

Every batch of 1-(4-Bromo-3-Chlorophenyl)Propan-1-One is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure it meets the high standards required for research and commercial synthesis. Our products are characterized by multiple spectroscopic and chromatographic techniques to guarantee identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition. The container should be kept tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.