Description

1-Bromo-3-(Bromomethyl)-5-Iodobenzene, also known as Alpha,3-Dibromo-5-Iodotoluene, is a high-value, multi-halogenated aromatic building block of significant importance in advanced organic synthesis. Its precise molecular architecture, featuring bromine and iodine substituents at strategic positions, makes it an indispensable intermediate for constructing complex molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in cross-coupling reactions and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science & OLED Development: Serves as a building block for creating organic semiconductors, liquid crystals, and ligands for metal-organic frameworks (MOFs) due to its ability to facilitate electron transfer and structural diversity.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Negishi couplings, where the iodine and bromine atoms offer orthogonal reactivity for sequential functionalization.
• Chemical Research & Development: Employed in academic and industrial R&D for method development, catalyst testing, and exploring new synthetic pathways in medicinal chemistry.

Basic Information

Product Name	1-Bromo-3-(Bromomethyl)-5-Iodobenzene / Alpha,3-Dibromo-5-Iodotoluene
CAS No.	1261553-05-2
Molecular Formula	C7H5Br2I
Molecular Weight	375.83 g/mol
Synonyms	3-(Bromomethyl)-1-bromo-5-iodobenzene; 1-Bromo-3-(bromomethyl)-5-iodo-benzene; α,3-Dibromo-5-iodotoluene; 5-Iodo-α,3-dibromotoluene; Benzene, 1-bromo-3-(bromomethyl)-5-iodo-; 3-Bromomethyl-5-iodo-1-bromobenzene; (3-Bromo-5-iodophenyl)methyl bromide
EINECS	Contact for details

Quality Control

Our 1-Bromo-3-(Bromomethyl)-5-Iodobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided to guarantee consistency and reliability for your critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.