Description

2-Bromo-1-Chloro-4-(Ethylcarbonyl)Benzene is a high-purity, halogenated aromatic ketone building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both bromine and chlorine substituents adjacent to an acetyl group, makes it a versatile and valuable intermediate for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring specific halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the halogenated benzene core is essential for bioactivity.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The bromine and chlorine atoms offer orthogonal reactivity for sequential metal-catalyzed cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination.
• Chemical Derivatization: The acetyl (ethylcarbonyl) group can be further functionalized through reduction, oxidation, or condensation reactions to create a diverse library of derivatives.
• Laboratory Scale R&D: Supplied to academic and industrial research laboratories for method development and exploratory chemistry projects.

Basic Information

Product Name	2-Bromo-1-Chloro-4-(Ethylcarbonyl)Benzene
CAS No.	1261527-19-8
Molecular Formula	C9H8BrClO
Molecular Weight	247.52 g/mol
Synonyms	1-Bromo-2-Chloro-4-Acetylbenzene; 4-Acetyl-2-Bromo-1-Chlorobenzene; 2-Bromo-1-Chloro-4-Acetylbenzene; 4-Acetyl-2-Bromochlorobenzene; 2-Bromo-4-Acetylchlorobenzene; 1-Chloro-2-Bromo-4-Acetylbenzene; (2-Bromo-1-Chloro-4-phenyl) Ethyl Ketone; 4-Acetyl-2-bromo-1-chloro-benzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-1-Chloro-4-(Ethylcarbonyl)Benzene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports critical R&D and scale-up activities where material integrity is paramount.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.