Description

1-(2-Bromo-4-Chlorophenyl)Propan-1-One is a high-purity organic building block and key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or possessing specific receptor-binding profiles.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the bromo and chloro substituents offer unique reactivity for creating potent bioactive molecules.
• Material Science Research: Serves as a precursor for the development of advanced organic materials, including liquid crystals, polymers, and organic semiconductors, leveraging its aromatic ketone functionality.
• Chemical Biology & Proteomics: Employed as a scaffold or linker in the design of chemical probes, enzyme inhibitors, and activity-based protein profiling (ABPP) agents for target identification and validation.
• Academic & Contract Research: A valuable reagent for methodological development in organic synthesis, including cross-coupling reactions, carbonyl chemistry, and halogenation studies.

Basic Information

Product Name	1-(2-Bromo-4-Chlorophenyl)Propan-1-One
CAS No.	1261527-08-5
Molecular Formula	C9H8BrClO
Molecular Weight	247.52 g/mol
Synonyms	2-Bromo-4-Chloropropiophenone; 1-Propanone, 1-(2-bromo-4-chlorophenyl)-; 2'-Bromo-4'-chloropropiophenone; (2-Bromo-4-chlorophenyl) propan-1-one; 2-Bromo-4-chloro-1-propiophenone; α-Bromo-4-chloropropiophenone (ambiguous, verify structure); Propiophenone, 2-bromo-4'-chloro-
EINECS	Contact for details

Quality Control

Our 1-(2-Bromo-4-Chlorophenyl)Propan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.