Description

3-Iodo-4-(Trifluoromethyl)Benzyl Bromide is a high-value, multi-functional halogenated aromatic building block. This compound is critical for introducing both iodine and bromine functional groups into complex molecular architectures, enabling advanced synthetic transformations. It is primarily sought after by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for applications in cross-coupling reactions, medicinal chemistry, and the synthesis of liquid crystal materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in oncology and CNS research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging the stability of the trifluoromethyl group.
• Cross-Coupling Reactions: Serves as a versatile substrate in Suzuki, Stille, and Negishi couplings due to the reactive iodine and benzyl bromide moieties.
• Material Science: Precursor for organic electronic materials, including organic light-emitting diodes (OLEDs) and liquid crystals.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies and the introduction of halogen atoms for metabolic stability.
• Chemical Biology: Used in the synthesis of probes and tags for bioconjugation and imaging applications.

Basic Information

Product Name	3-Iodo-4-(Trifluoromethyl)Benzyl Bromide
CAS No.	1261482-51-2
Molecular Formula	C8H5BrF3I
Molecular Weight	374.93 g/mol
Synonyms	1-(Bromomethyl)-3-iodo-4-(trifluoromethyl)benzene; α-Bromo-3-iodo-4-(trifluoromethyl)toluene; (3-Iodo-4-(trifluoromethyl)phenyl)methyl bromide; 3-Iodo-α-bromo-4-(trifluoromethyl)toluene; 4-(Bromomethyl)-2-iodobenzotrifluoride
EINECS	Contact for details

Quality Control

Our 3-Iodo-4-(Trifluoromethyl)Benzyl Bromide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to meet the stringent requirements of research and development as well as scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥96.0%
Melting Point	Contact for details
Heavy Metals	<10 ppm
Residual Solvents	Complies with ICH guidelines
Water Content (KF)	<0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.