Description

2-Iodo-3-Nitrobenzonitrile is a versatile halogenated aromatic nitrile building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both an electron-withdrawing nitro group and a reactive iodine substituent, makes it a critical intermediate for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel chemical entities through cross-coupling and functional group transformation reactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for molecules requiring a halogenated aromatic core.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science Research: Serves as a building block for creating specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: The iodine atom is highly reactive in palladium-catalyzed couplings (e.g., Suzuki, Sonogashira, Heck reactions) to form new carbon-carbon bonds.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Acts as a starting material for synthesizing molecular probes and tags used in biochemical research.

Basic Information

Product Name	2-Iodo-3-Nitrobenzonitrile
CAS No.	1261481-69-9
Molecular Formula	C7H3IN2O2
Molecular Weight	273.97 g/mol
Synonyms	3-Nitro-2-iodobenzonitrile; 2-Iodo-3-nitrobenzenecarbonitrile; Benzonitrile, 2-iodo-3-nitro-; 2-Iodo-3-nitro-benzonitrile; 2-Iodo-3-nitrobenzonitrile (CAS 1261481-69-9)
EINECS	Contact for details

Quality Control

Our 2-Iodo-3-Nitrobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and cGMP manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.