Description

4-Bromo-2-Propanoyl-1-(Trifluoromethoxy)Benzene is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated and trifluoromethoxy-substituted aromatic structure. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with enhanced metabolic stability and bioavailability. It is primarily utilized by R&D laboratories and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new therapeutic agents and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and pesticides, leveraging the biological activity of the trifluoromethoxy group.
• Material Science: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its aromatic and halogenated properties.
• Chemical Synthesis: Acts as a versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and functional group transformations in complex organic synthesis.
• Life Science R&D: Employed in academic and industrial research laboratories for probing biochemical pathways and developing molecular probes.

Basic Information

Product Name	4-Bromo-2-Propanoyl-1-(Trifluoromethoxy)Benzene
CAS No.	1261439-45-5
Molecular Formula	C10H8BrF3O2
Molecular Weight	297.07 g/mol
Synonyms	1-Bromo-4-(trifluoromethoxy)-2-propiophenone; 2-Propanoyl-4-bromo-1-(trifluoromethoxy)benzene; 4-Bromo-2-propionyl-1-(trifluoromethoxy)benzene; 4-Bromo-α-ethyl-2-(trifluoromethoxy)acetophenone; 2-Propiophenone, 4'-bromo-2'-(trifluoromethoxy)-; 4-Bromo-2-propionyl-1-(trifluoromethoxy)benzene; 4-Bromo-2-(1-oxopropyl)-1-(trifluoromethoxy)benzene
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Propanoyl-1-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for advanced R&D and cGMP-compliant production environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere after each use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.