Description

4-Chloro-3-Fluoropyridine-2-Carbaldehyde is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its unique halogenated pyridine structure makes it a critical intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for biochemical and diagnostic research applications.

Basic Information

Product Name	4-Chloro-3-Fluoropyridine-2-Carbaldehyde
CAS No.	1260878-78-1
Molecular Formula	C6H3ClFNO
Molecular Weight	159.54 g/mol
Synonyms	2-Formyl-4-chloro-3-fluoropyridine; 4-Chloro-3-fluoro-2-pyridinecarboxaldehyde; 4-Chloro-3-fluoropyridine-2-carboxaldehyde; 3-Fluoro-4-chloropyridine-2-carbaldehyde; 2-Pyridinecarboxaldehyde, 4-chloro-3-fluoro-; 4-Chloro-3-fluoro-2-formylpyridine
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Fluoropyridine-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed specifications for every shipment, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider an inert atmosphere. Keep away from strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.