Description

1-(4-Amino-2,3,5-Trifluoro-Phenyl)-Ethanone is a high-purity fluorinated aromatic ketone building block, essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Industries requiring precise and reliable fluorinated intermediates for research and production, such as medicinal chemistry and specialty chemical manufacturing, need this high-quality material.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides, where the trifluoromethyl and amino groups contribute to biological activity and stability.
• Material Science Research: Serves as a precursor for advanced polymers and liquid crystals, leveraging its aromatic and fluorine-containing structure to modify material properties.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination, to introduce complex aromatic systems into target molecules.
• Fluorine Chemistry Studies: A valuable compound for academic and industrial research focused on understanding and applying fluorination effects in molecular design.

Basic Information

Product Name	1-(4-Amino-2,3,5-Trifluoro-Phenyl)-Ethanone
CAS No.	1260764-37-1
Molecular Formula	C8H5F3NO
Molecular Weight	188.13 g/mol
Synonyms	1-(4-Amino-2,3,5-trifluorophenyl)ethanone; 2,3,5-Trifluoro-4-acetylaniline; 4-Acetylamino-2,3,5-trifluorobenzene; 4-Amino-2,3,5-trifluoroacetophenone; Ethanone, 1-(4-amino-2,3,5-trifluorophenyl)-; 4-Acetyl-2,3,5-trifluoroaniline; 2,3,5-Trifluoro-4-aminophenylethanone
EINECS	Contact for details

Quality Control

Our 1-(4-Amino-2,3,5-Trifluoro-Phenyl)-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.