Description

2,4,5-Trifluorophenethyl Bromide is a high-value fluorinated aromatic building block essential for advanced organic synthesis. This compound matters for its role as a versatile intermediate in the creation of complex molecules with tailored properties, particularly within the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), liquid crystal materials, and novel agrochemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, including kinase inhibitors and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides where the trifluoromethylphenethyl moiety enhances biological activity and metabolic stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated mesogens, improving the dielectric anisotropy and stability of display components.
• Organic Electronics: Employed in the synthesis of fluorinated organic semiconductors and charge-transport materials for OLEDs and OFETs.
• Cross-Coupling Reactions: The bromide moiety makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Negishi, and Kumada couplings to form complex biaryl structures.
• Chemical Research & Development: A valuable reagent for exploring new fluorination strategies and constructing diverse chemical libraries for screening.

Basic Information

Product Name	2,4,5-Trifluorophenethyl Bromide
CAS No.	1260764-09-7
Molecular Formula	C8H6BrF3
Molecular Weight	247.04 g/mol
Synonyms	1-(2-Bromoethyl)-2,4,5-trifluorobenzene; 2-(2,4,5-Trifluorophenyl)ethyl Bromide; (2,4,5-Trifluorophenyl)ethyl Bromide; 2-Bromoethyl-2,4,5-trifluorobenzene; 2,4,5-Trifluoro-β-bromoethylbenzene; β-Bromo-2,4,5-trifluorophenylethane
EINECS	Contact for details

Quality Control

Our 2,4,5-Trifluorophenethyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.