Description

3-(4-Fluorophenyl)Oxetan-3-Amine is a high-value, fluorinated oxetane amine building block of significant interest in modern synthetic chemistry. Its unique structure, featuring a strained oxetane ring and a primary amine group, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by pharmaceutical and agrochemical research organizations for the development of novel active ingredients, where its properties can be leveraged to modulate the physicochemical characteristics of lead compounds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the fluorine atom and oxetane moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials, where the oxetane ring can be utilized in polymerization reactions.
• Chemical Biology Probes: Useful for the design and synthesis of molecular probes and tags for studying biological systems.

Basic Information

Product Name	3-(4-Fluorophenyl)Oxetan-3-Amine
CAS No.	1260672-73-8
Molecular Formula	C9H10FNO
Molecular Weight	167.18 g/mol
Synonyms	3-Amino-3-(4-fluorophenyl)oxetane; 3-(4-Fluorophenyl)-3-oxetanamine; 3-(p-Fluorophenyl)oxetan-3-amine; 4-Fluoro-α-(oxetan-3-yl)benzenemethanamine; 1-(4-Fluorophenyl)-1-(oxetan-3-yl)methanamine; 3-(4-Fluorophenyl)oxetan-3-ylamine
EINECS	Contact for details

Quality Control

Our production of 3-(4-Fluorophenyl)Oxetan-3-Amine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.