Description

Ethyl 2-Chloro-1H-Imidazole-5-Carboxylate is a high-purity, versatile heterocyclic building block of significant importance in modern synthetic chemistry. Its core value lies in its functionalized imidazole ring, which serves as a critical intermediate for constructing complex molecules with targeted biological activity. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and enzyme inhibitors.
• Agrochemical Development: Used in the research and production of advanced fungicides, herbicides, and insecticides, leveraging the bioactivity of the chlorinated imidazole core.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized N-heterocyclic carbene (NHC) ligands and other organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, metal-organic frameworks (MOFs), and functional polymers.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom chemical synthesis services, supporting R&D projects and scale-up processes.
• Academic and Industrial Research: A valuable reagent for methodological studies in organic chemistry and for exploring new chemical spaces in medicinal chemistry programs.

Basic Information

Product Name	Ethyl 2-Chloro-1H-Imidazole-5-Carboxylate
CAS No.	1260670-74-3
Molecular Formula	C6H7ClN2O2
Molecular Weight	174.59 g/mol
Synonyms	2-Chloro-1H-imidazole-5-carboxylic acid ethyl ester; Ethyl 2-chloroimidazole-5-carboxylate; 5-Carbethoxy-2-chloroimidazole; 2-Chloro-5-ethoxycarbonylimidazole; 1H-Imidazole-5-carboxylic acid, 2-chloro-, ethyl ester; 1260670-74-3; Ethyl 2-chloro-1H-imidazole-5-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 2-Chloro-1H-Imidazole-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere if possible and opened only in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.