Description

2-(Boc-Amino)-5-Bromoisonicotinaldehyde is a high-purity, protected heterocyclic aldehyde building block used in advanced organic synthesis. This compound is valued for its dual functionality, offering both a reactive aldehyde group and a Boc-protected amine, enabling precise molecular construction. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of complex heterocyclic compounds and active pharmaceutical ingredients (APIs).
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides requiring specific brominated isonicotinaldehyde scaffolds.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands used in catalysis and material science.
• Peptidomimetics & Conjugates: The aldehyde functionality allows for conjugation and the creation of peptidomimetic structures in medicinal chemistry.
• Chemical Biology Probes: Useful for synthesizing labeled compounds and probes for studying biological mechanisms.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and novel synthetic route exploration.

Basic Information

Product Name	2-(Boc-Amino)-5-Bromoisonicotinaldehyde
CAS No.	1260667-46-6
Molecular Formula	C11H13BrN2O3
Molecular Weight	301.14 g/mol
Synonyms	5-Bromo-2-[(tert-butoxycarbonyl)amino]isonicotinaldehyde; 2-((tert-Butoxycarbonyl)amino)-5-bromoisonicotinaldehyde; 5-Bromo-2-(Boc-amino)isonicotinaldehyde; Boc-5-Bromo-2-aminoisonicotinaldehyde; 2-Amino-5-bromoisonicotinaldehyde N-Boc derivative; tert-Butyl (5-bromo-4-formylpyridin-2-yl)carbamate; CAS 1260667-46-6
EINECS	Contact for details

Quality Control

Our 2-(Boc-Amino)-5-Bromoisonicotinaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and our quality system supports the requirements for cGMP manufacturing of advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.