Description

5-(Trifluoromethyl)-1,3,4-Thiadiazole-2-Carbaldehyde is a high-value, fluorinated heterocyclic building block characterized by its reactive aldehyde group and electron-deficient thiadiazole core. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals, where the trifluoromethyl group enhances metabolic stability and bioavailability. Pharmaceutical, agrochemical, and advanced material researchers need this specialized intermediate to develop new drugs, crop protection agents, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for constructing novel drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research programs.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiadiazole moiety.
• Material Science: Serves as a precursor for functional polymers, liquid crystals, and organic electronic materials due to its unique electronic properties.
• Chemical Research: Employed in medicinal and synthetic chemistry for lead optimization and structure-activity relationship (SAR) studies.
• Coordination Chemistry: Acts as a ligand precursor for metal-organic frameworks (MOFs) and catalytic complexes.

Basic Information

Product Name	5-(Trifluoromethyl)-1,3,4-Thiadiazole-2-Carbaldehyde
CAS No.	1260667-41-1
Molecular Formula	C4HF3N2OS
Molecular Weight	182.12 g/mol
Synonyms	2-Formyl-5-(trifluoromethyl)-1,3,4-thiadiazole; 1,3,4-Thiadiazole-2-carboxaldehyde, 5-(trifluoromethyl)-; 5-(Trifluoromethyl)-1,3,4-thiadiazole-2-carboxaldehyde; 5-Trifluoromethyl-1,3,4-thiadiazole-2-carbaldehyde; 5-Trifluoromethyl-2-formyl-1,3,4-thiadiazole; TFMT-Carbaldehyde
EINECS	Contact for details

Quality Control

Our 5-(Trifluoromethyl)-1,3,4-Thiadiazole-2-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.