Description

6-Bromo-4-Hydroxynicotinaldehyde is a versatile and highly functionalized pyridine derivative, serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in the strategic positioning of reactive bromo, hydroxyl, and aldehyde functional groups, enabling precise molecular construction for complex target molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries who require high-purity building blocks for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in developing new herbicides, fungicides, and plant growth regulators due to its bioactive pyridine core.
• Ligand and Catalyst Synthesis: Serves as a building block for creating complex chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Employed in the research and development of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology: Utilized as a probe or linker in bioconjugation chemistry and the development of chemical tools for biological study.
• Custom Synthesis & Scale-up: A starting material for contract research organizations (CROs) and CDMOs engaged in custom synthesis projects from milligram to kilogram scale.

Basic Information

Product Name	6-Bromo-4-Hydroxynicotinaldehyde
CAS No.	1260665-55-1
Molecular Formula	C7H4BrNO2
Molecular Weight	214.02 g/mol
Synonyms	4-Hydroxy-6-bromonicotinaldehyde; 6-Bromo-4-hydroxypyridine-3-carboxaldehyde; 3-Formyl-6-bromo-4-hydroxypyridine; 6-Bromo-4-pyridinol-3-carboxaldehyde; 4-Hydroxy-6-bromo-3-pyridinecarboxaldehyde; 6-Bromo-4-hydroxy-3-pyridinecarbaldehyde; 6-Bromo-4-hydroxynicotinic aldehyde
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-4-Hydroxynicotinaldehyde is produced and analyzed under strict quality management protocols to ensure consistency and reliability for your research and development. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with stringent purity specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.