Description

3-Oxoisoindoline-5-Carbaldehyde is a versatile and high-value organic building block characterized by its fused isoindolinone core and reactive aldehyde functionality. This compound matters for its critical role as a key intermediate in the synthesis of complex heterocyclic compounds and active pharmaceutical ingredients (APIs). It is primarily needed by research chemists and process development teams in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of isoindolinone-based drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides with isoindolinone scaffolds.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and host materials in OLED displays and lighting.
• Ligand and Catalyst Development: The aldehyde group allows for the creation of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Polymer and Material Science: Incorporated into specialty polymers to modify thermal stability, solubility, and optical properties.
• Academic and R&D: Employed in medicinal chemistry research for structure-activity relationship (SAR) studies and library synthesis.

Basic Information

Product Name	3-Oxoisoindoline-5-Carbaldehyde
CAS No.	1260664-94-5
Molecular Formula	C9H7NO2
Molecular Weight	161.16 g/mol
Synonyms	5-Formyl-2,3-dihydro-1H-isoindol-1-one; 5-Formylisoindolin-1-one; 1-Oxo-2,3-dihydro-1H-isoindole-5-carboxaldehyde; Isoindolin-1-one, 5-formyl-2,3-dihydro-; 5-Carbaldehyde-3-oxoisoindoline; 3-Oxo-2,3-dihydro-1H-isoindole-5-carbaldehyde
EINECS	Contact for details

Quality Control

Our 3-Oxoisoindoline-5-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. This material is easily oxidized and light-sensitive; prolonged exposure to air or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.