Description

2-Chloro-4-(1,3-Dioxolan-2-Yl)Pyridine is a high-value, multi-functional heterocyclic building block used in advanced organic synthesis. Its core value lies in the reactive chloropyridine moiety and the protected aldehyde functionality of the dioxolane group, enabling precise molecular construction. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides requiring specific pyridine-based scaffolds.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic electronic materials and functionalized polymers.
• Chemical Biology Probes: Useful for creating tagged molecules for studying biological pathways and target engagement.

Basic Information

Product Name	2-Chloro-4-(1,3-Dioxolan-2-Yl)Pyridine
CAS No.	1260664-72-9
Molecular Formula	C8H8ClNO2
Molecular Weight	185.61 g/mol
Synonyms	2-Chloro-4-(1,3-dioxolan-2-yl)pyridine; 4-(1,3-Dioxolan-2-yl)-2-chloropyridine; 2-Chloro-4-(1,3-dioxolan-2-yl)pyridine; 2-Chloro-4-(2',5'-dihydro-1',4'-dioxin-2'-yl)pyridine (tautomer consideration); Pyridine, 2-chloro-4-(1,3-dioxolan-2-yl)-; Building Block 1260664-72-9
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(1,3-Dioxolan-2-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization using HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.