Description

trans-2-Iodovinylboronic Acid Mida Ester is a high-value, protected boronic acid derivative designed for advanced cross-coupling reactions. This compound is crucial for its enhanced stability and controlled reactivity, which facilitates complex synthetic pathways with high selectivity and yield. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing novel molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key building block in Suzuki-Miyaura cross-coupling reactions for constructing complex drug candidates, especially those containing vinyl-iodide or vinyl-boronate functional groups.
• Agrochemical Research: Used in the development of novel active ingredients by enabling the formation of carbon-carbon bonds in complex heterocyclic or aromatic systems.
• Material Science & OLED Development: Serves as a precursor for creating conjugated organic molecules and polymers used in electronic devices and light-emitting materials.
• Chemical Biology & Probe Development: Utilized in the synthesis of bioconjugates and molecular probes where the Mida ester protecting group allows for sequential, chemoselective functionalization.
• Academic & Industrial R&D: An essential reagent for methodological development in organic synthesis and catalysis research.

Basic Information

Product Name	trans-2-Iodovinylboronic Acid Mida Ester
CAS No.	1260504-68-4
Molecular Formula	C9H12BINO3
Molecular Weight	334.91 g/mol
Synonyms	trans-2-Iodovinyl MIDA Boronate; (E)-2-(2-Iodovinyl)-1,3,2-dioxaborolane-4,6-dione; N-Methyliminodiacetic Acid (MIDA) Boronate Ester of trans-2-Iodovinylboronic Acid; (E)-2-(2-Iodovinyl)-5-methyl-1,3,2-dioxaborolane-4,6-dione; trans-β-Iodovinyl MIDA Boronate; Vinyl Iodide MIDA Ester; B-(2-Iodoethenyl)-N-methyliminodiacetic acid boronate
EINECS	Contact for details

Quality Control

Our trans-2-Iodovinylboronic Acid Mida Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized by NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere. This compound is hygroscopic (moisture-sensitive) and light-sensitive; prolonged exposure to air, moisture, or light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95%
Isomeric Purity (trans/cis ratio)	≥98:2
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.