Description

4-Fluoropyridine-2-Boronic Acid Pinacol Ester is a high-value organoboron building block crucial for modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone method for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to introduce the 4-fluoropyridin-2-yl moiety into target structures, facilitating the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, receptor modulators, and other small-molecule drugs.
• Agrochemical Research: Used in creating novel herbicides, fungicides, and insecticides by constructing complex heterocyclic cores.
• Material Science: Serves as a precursor for synthesizing functional organic materials, such as ligands for catalysts or components for organic electronics.
• Chemical Biology: Employed in the design and synthesis of molecular probes and bio-conjugates for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical suppliers and CROs/CMOs offering bespoke synthesis services.

Basic Information

Product Name	4-Fluoropyridine-2-Boronic Acid Pinacol Ester
CAS No.	1260152-43-9
Molecular Formula	C11H15BFNO2
Molecular Weight	223.05 g/mol
Synonyms	2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-fluoropyridine; 4-Fluoro-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-Fluoropyridine-2-boronic acid pinacol ester; 4-Fluoro-2-pyridineboronic acid pinacol ester; (4-Fluoropyridin-2-yl)boronic acid pinacol ester; Pinacol 4-fluoropyridine-2-boronate
EINECS	Contact for details

Quality Control

Our 4-Fluoropyridine-2-Boronic Acid Pinacol Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.