Description

2-Hydroxy-8-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Naphthalene is a high-value, functionalized naphthalene derivative containing a pinacol boronate ester group. This compound matters as a versatile and critical organic synthetic intermediate, prized for its role in facilitating carbon-carbon bond formation via cross-coupling reactions. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key building block for synthesizing biaryl and heterobiaryl structures prevalent in active pharmaceutical ingredients (APIs) and functional materials.
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, particularly those requiring extended aromatic or conjugated systems.
• Agrochemical Synthesis: Employed in creating advanced herbicides, fungicides, and insecticides with tailored properties.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials and emissive layer components in display and lighting technologies.
• Ligand Synthesis for Catalysis: Useful for preparing sophisticated bidentate or polydentate ligands used in homogeneous catalysis.
• Material Science Research: A precursor for organic semiconductors, conductive polymers, and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Can be utilized to create boronic acid-based sensors and probes for detecting sugars or other biological analytes.

Basic Information

Item	Detail
Product Name	2-Hydroxy-8-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Naphthalene
CAS No.	1260151-69-6
Molecular Formula	C₁₆H₂₁BO₃
Molecular Weight	272.15 g/mol
Synonyms	8-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-naphthol; 2-Naphthol-8-boronic acid pinacol ester; 8-Borono-2-naphthol pinacol ester; 2-Hydroxy-8-naphthaleneboronic acid pinacol ester; 8-(Pinacolatoboryl)-2-naphthol; 2-Naphthol-8-ylboronic acid pinacol ester; 8-(2-Hydroxynaphthyl)pinacolboronate
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-8-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Naphthalene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.