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2-Phenyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine CAS NO 1260106-29-3


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CAS No.:1260106-29-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Phenyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value organoboron building block, specifically a pyridine-substituted boronic ester, widely used in advanced organic synthesis. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors who require reliable, high-purity intermediates for drug discovery, ligand synthesis, and functional material development.

Application

  • Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing biphenyl or heterobiaryl motifs.
  • Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require specific aryl-pyridine structures.
  • Material Science & OLED Development: Serves as a precursor for creating organic light-emitting diode (OLED) materials, electronic chemicals, and advanced polymers.
  • Ligand & Catalyst Preparation: Employed in the synthesis of specialized ligands for catalysis and metal-organic frameworks (MOFs).
  • Academic & Contract Research: A vital reagent for methodology development and complex molecule construction in research laboratories and CROs (Contract Research Organizations).
  • Fine Chemical Production: Integral to the multi-step synthesis of specialty and performance chemicals.

Basic Information

Item Details
Product Name 2-Phenyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No. 1260106-29-3
Molecular Formula C17H20BNO2
Molecular Weight 281.16 g/mol
Synonyms 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-phenylpyridine; 2-Phenyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Phenylpyridine-5-boronic acid pinacol ester; (2-Phenylpyridin-5-yl)boronic acid pinacol ester; 5-(2-Phenylpyridin-5-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
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Quality Control

Every batch of our 2-Phenyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine undergoes rigorous analytical testing to ensure it meets the stringent requirements of advanced synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality management system is designed to support cGMP and ISO standards for traceability and consistency, making this product suitable for regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥97.0% (Area %)
Water Content (KF) ≤0.5%
Residue on Ignition ≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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