Description

6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)benzo[d]oxazol-2-amine is a high-purity, heterocyclic boronic ester derivative that serves as a critical building block in modern synthetic chemistry. This compound is valued for its role as a versatile intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Building block for creating organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and activity-based protein profiling (ABPP) reagents.
• Ligand Synthesis: Intermediate for the preparation of sophisticated ligands used in catalysis and metal-organic frameworks (MOFs).
• Academic & Contract Research: Essential reagent for methodological development in organic synthesis and medicinal chemistry programs.

Basic Information

Product Name	6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)benzo[d]oxazol-2-amine
CAS No.	1260091-04-0
Molecular Formula	C15H21BN2O3
Molecular Weight	288.15 g/mol
Synonyms	2-Amino-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoxazole; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-benzoxazolamine; 2-Benzoxazolamine, 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; Benzo[d]oxazol-2-amine, 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 6-(Pinacolatoboran-2-yl)benzo[d]oxazol-2-amine; 6-(Pinacolatoboryl)-2-benzoxazolamine
EINECS	Contact for details

Quality Control

Our 6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)benzo[d]oxazol-2-amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.