Description

6-(Trifluoromethoxy)-3,4-Dihydronaphthalen-1(2H)-One is a high-value, fluorinated organic building block characterized by its unique naphthalenone core modified with a trifluoromethoxy substituent. This compound matters as a critical synthetic intermediate, offering pharmaceutical and agrochemical researchers a versatile scaffold for developing novel active ingredients with enhanced metabolic stability and bioavailability. It is primarily needed by R&D and process chemistry teams in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research pipelines.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides where the trifluoromethoxy group imparts improved lipophilicity and biological activity.
• Material Science Research: Acts as a monomer or building block for creating specialty polymers and organic electronic materials with specific optical or electronic properties.
• Chemical Biology Probes: Employed in the design and synthesis of fluorinated probes and tags for studying biological mechanisms and enzyme interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the fine chemical industry.

Basic Information

Product Name	6-(Trifluoromethoxy)-3,4-Dihydronaphthalen-1(2H)-One
CAS No.	1260019-45-1
Molecular Formula	C11H9F3O2
Molecular Weight	230.18 g/mol
Synonyms	6-(Trifluoromethoxy)-3,4-dihydro-1(2H)-naphthalenone; 6-(Trifluoromethoxy)-1-tetralone; 1-Tetralone, 6-(trifluoromethoxy)-; 6-(Trifluoromethoxy)-3,4-dihydronaphthalen-1-one; 6-Trifluoromethoxy-1-tetralone; 6-(Trifluoromethoxy)-1-oxo-1,2,3,4-tetrahydronaphthalene; FMO-Tetralone
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethoxy)-3,4-Dihydronaphthalen-1(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.