Description

6-Bromo-7-Fluoro-2,3-Dihydro-1H-Inden-1-One is a high-purity, halogenated indanone derivative serving as a critical advanced intermediate in modern organic synthesis. Its unique bromo-fluoro substitution pattern on the aromatic ring makes it a valuable scaffold for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the halogen atoms can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe Development: Utilized to create molecular probes and tags for studying enzyme function and biological pathways due to its reactive ketone and halogen handles.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development, heterocyclic chemistry, and structure-activity relationship (SAR) studies.

Basic Information

Item	Details
Product Name	6-Bromo-7-Fluoro-2,3-Dihydro-1H-Inden-1-One
CAS No.	1260012-83-6
Molecular Formula	C9H6BrFO
Molecular Weight	229.05 g/mol
Synonyms	6-Bromo-7-fluoroindan-1-one; 1H-Inden-1-one, 6-bromo-7-fluoro-2,3-dihydro-; 6-Bromo-7-fluoro-2,3-dihydro-1H-inden-1-one; 6-Bromo-7-fluoroindanone; 7-Fluoro-6-bromo-2,3-dihydro-1H-inden-1-one
EINECS	Contact for details

Quality Control

Every batch of 6-Bromo-7-Fluoro-2,3-Dihydro-1H-Inden-1-One is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and consistency for your research and development processes. A detailed Certificate of Analysis (COA), including purity assay and impurity profile determined by HPLC, is supplied with each shipment to guarantee it meets your specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.