Description

5-Bromo-8-Fluoro-2,3,4-Tri Hydronaphthalen-1-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated naphthalenone structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs) where precise molecular architecture is required for biological activity. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Serves as a precursor for developing new-generation herbicides and pesticides with specific modes of action.
• Material Science: Used in the research and development of organic electronic materials and specialty polymers.
• Chemical Synthesis: Acts as a versatile reagent for introducing bromo and fluoro substituents in complex organic molecules via cross-coupling reactions.
• Academic & R&D: Employed in university and corporate laboratories for methodological studies in synthetic organic chemistry.

Basic Information

Item	Details
Product Name	5-Bromo-8-Fluoro-2,3,4-Tri Hydronaphthalen-1-One
CAS No.	1260010-73-8
Molecular Formula	C₁₀H₈BrFO
Molecular Weight	243.08 g/mol
Synonyms	5-Bromo-8-fluoro-1,2,3,4-tetrahydronaphthalen-1-one; 5-Bromo-8-fluoro-3,4-dihydro-2H-naphthalen-1-one; 8-Fluoro-5-bromo-3,4-dihydro-1(2H)-naphthalenone; 1(2H)-Naphthalenone, 5-bromo-8-fluoro-3,4-dihydro-; 5-Bromo-8-fluoro-1-tetralone
EINECS	Contact for details

Quality Control

Our production of 5-Bromo-8-Fluoro-2,3,4-Tri Hydronaphthalen-1-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are manufactured under cGMP-like conditions suitable for pharmaceutical research applications. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed when not in use to prevent contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.