Description

Methyl 1-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl]cyclopropane-1-carboxylate is a high-value, multifunctional boronic ester derivative designed for advanced synthetic chemistry. This compound is a critical building block in modern organic synthesis, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for the development of novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a key arylboronate ester coupling partner for the synthesis of biaryl and heterobiaryl structures, a cornerstone reaction in medicinal chemistry.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing cyclopropane and biphenyl motifs.
• Agrochemical Synthesis: Employed as a precursor in the creation of novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Acts as a starting material for synthesizing specialized ligands and organometallic catalysts.
• Materials Science Research: Utilized in the development of organic electronic materials, such as OLEDs and semiconductors, where precise molecular structure is critical.
• Chemical Biology Probes: Incorporated into molecular probes for studying biological processes and target engagement.

Basic Information

Item	Details
Product Name	Methyl 1-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl]cyclopropane-1-carboxylate
CAS No.	1259022-88-2
Molecular Formula	C17H23BO4
Molecular Weight	302.18 g/mol
Synonyms	Methyl 1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropanecarboxylate; 1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)cyclopropanecarboxylic acid methyl ester; 4-(Methoxycarbonyl)cyclopropyl)phenylboronic acid pinacol ester; (4-(Methoxycarbonyl)cyclopropyl)phenylboronic acid pinacol ester; Cyclopropanecarboxylic acid, 1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 1-[4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-yl)phenyl]cyclopropane-1-carboxylate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical characterization, including HPLC, NMR (1H, 13C, 11B), and GC/MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C to minimize hydrolysis and oxidation. The container should be kept tightly sealed in a desiccated environment due to its hygroscopic nature. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.