Description

1-Boc-4-(3-Formylphenyl)Piperazine is a high-purity, protected piperazine derivative featuring a formylphenyl substituent, serving as a critical building block in modern organic synthesis. This compound is essential for medicinal chemistry research and development, providing a versatile scaffold for the creation of novel pharmaceutical candidates. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules and exploring new therapeutic pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) due to its reactive aldehyde and protected amine functionalities.
• Peptidomimetics: Serves as a building block for the design and synthesis of peptidomimetic compounds, modulating biological activity and stability.
• Agrochemical Development: Utilized in the research and synthesis of novel crop protection agents and herbicides.
• Chemical Biology Probes: Acts as a starting material for creating labeled probes or affinity tags to study biological systems and protein interactions.

Basic Information

Product Name	1-Boc-4-(3-Formylphenyl)Piperazine
CAS No.	1257849-25-4
Molecular Formula	C16H22N2O3
Molecular Weight	290.36 g/mol
Synonyms	1-Boc-4-(3-Formylphenyl)piperazine; tert-Butyl 4-(3-formylphenyl)piperazine-1-carboxylate; 4-(3-Formylphenyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; 1-(tert-Butoxycarbonyl)-4-(3-formylphenyl)piperazine; N-Boc-4-(3-formylphenyl)piperazine; 3-(4-(tert-Butoxycarbonyl)piperazin-1-yl)benzaldehyde; 1-Boc-4-(3-carboxaldehydephenyl)piperazine
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(3-Formylphenyl)Piperazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.