Description

(R)-n-Boc-Morpholine-2-Acetic Acid CAS NO 1257848-48-8 is a high-purity, chiral building block of significant importance in modern synthetic organic chemistry. Its value lies in its role as a key intermediate for constructing complex molecules with defined stereochemistry, which is critical for biological activity. This compound is primarily needed by pharmaceutical research and development organizations, agrochemical innovators, and advanced material scientists for applications in drug discovery, process chemistry, and the synthesis of specialty chemicals.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and other therapeutic areas.
• Peptidomimetics & Bioactive Molecule Synthesis: Used to incorporate the morpholine-2-acetic acid scaffold into peptide backbones and other bioactive compounds to modulate pharmacokinetic properties.
• Asymmetric Catalysis & Ligand Development: Serves as a precursor for chiral ligands and organocatalysts used in enantioselective synthesis.
• Agrochemical Research: Employed in the development of novel, stereochemically pure pesticides and herbicides.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring high stereochemical fidelity at scale.

Basic Information

Product Name	(R)-n-Boc-Morpholine-2-Acetic Acid
CAS No.	1257848-48-8
Molecular Formula	C11H19NO5
Molecular Weight	245.27 g/mol
Synonyms	(R)-2-((tert-Butoxycarbonyl)amino)-2-morpholinoacetic acid; (R)-2-(Boc-amino)-2-morpholineacetic acid; (R)-N-Boc-morpholine-2-acetic acid; (2R)-2-[(tert-Butoxycarbonyl)amino]-2-morpholin-4-ylacetic acid; (R)-2-(tert-Butoxycarbonylamino)-2-morpholinoacetic acid; (R)-Boc-Morpholine-2-AcOH; (R)-Boc-Mor-OH(2); tert-Butyl (R)-(2-morpholino-2-oxoethyl)carbamate (tautomeric form)
EINECS	Contact for details

Quality Control

Our (R)-n-Boc-Morpholine-2-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity standards for research and development. Certificates of Analysis (COA) detailing identity, purity (typically ≥97% by HPLC), enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.