Description

3-Pyridineboronic Acid Mida Ester is a specialized, protected boronic acid derivative designed for advanced synthetic applications. This compound matters because it offers superior stability and handling characteristics compared to its free boronic acid counterpart, making it a valuable building block for complex molecule assembly. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing pyridine-containing scaffolds via cross-coupling reactions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) containing the pyridine moiety, particularly for kinase inhibitors and other small molecule drugs.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a stable, air- and moisture-tolerant coupling partner for the palladium-catalyzed formation of carbon-carbon bonds, enabling the construction of biaryl systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate pyridine-based structures.
• Material Science Research: Employed in the creation of organic ligands for catalysts or as a precursor for functionalized polymers and organic electronic materials.
• Chemical Biology & Probe Development: Utilized for the site-specific modification of biomolecules or the synthesis of chemical probes for biological target identification.
• Process Chemistry & Scale-up: Its enhanced stability makes it suitable for optimizing and scaling up synthetic routes in pilot plants and manufacturing settings.

Basic Information

Product Name	3-Pyridineboronic Acid Mida Ester
CAS No.	1257740-56-9
Molecular Formula	C9H11BN2O3
Molecular Weight	206.01 g/mol
Synonyms	3-Pyridinylboronic acid N-methyliminodiacetic acid ester; 3-Pyridylboronic Acid MIDA Ester; (3-Pyridinyl)-N-methyliminodiacetic acid boronate; 3-Pyridineboronic Acid MIDA Ester; MIDA Boronate of 3-Pyridineboronic Acid; 3-Pyridyl MIDA Boronate; CAS 1257740-56-9
EINECS	Contact for details

Quality Control

Our 3-Pyridineboronic Acid Mida Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with high-purity research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.