Description

2-Cyanophenylboronic Acid Mida Ester is a specialized, protected boronic acid derivative designed for advanced synthetic chemistry. This compound matters because the Mida (N-methyliminodiacetic acid) ester group provides exceptional stability, preventing protodeboronation and enabling complex, multi-step transformations under a wide range of conditions. It is a critical building block for researchers and manufacturers in pharmaceutical development, agrochemical synthesis, and materials science, particularly for constructing complex biaryl systems via Suzuki-Miyaura cross-coupling reactions.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing biphenyl or heterobiaryl scaffolds.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science & OLED Development: Building block for creating organic electronic materials, liquid crystals, and light-emitting compounds for display technologies.
• Cross-Coupling Reactions: A stable, air- and moisture-tolerant reagent for reliable Suzuki-Miyaura cross-coupling, enabling the formation of carbon-carbon bonds between aromatic rings.
• Chemical Biology & Probe Development: Useful for synthesizing molecular probes and bioconjugates where a stable boronic acid handle is required for later-stage functionalization.
• Library Synthesis for Drug Discovery: Enables the efficient, parallel synthesis of diverse compound libraries for high-throughput screening in medicinal chemistry.

Basic Information

Product Name	2-Cyanophenylboronic Acid Mida Ester
CAS No.	1257739-16-4
Molecular Formula	C₁₂H₁₁BN₂O₄
Molecular Weight	258.04 g/mol
Synonyms	2-Cyanophenyl MIDA Boronate; (2-Cyanophenyl)-MIDA-boronate; 2-Cyanobenzene MIDA Boronic Ester; 2-Cyanophenylboronic Acid N-Methyliminodiacetic Acid Ester; Boronic acid, B-(2-cyanophenyl)-, N-methyliminodiacetate ester; MIDA Boronate of 2-Cyanophenylboronic Acid; 2-CN-Ph-B(MIDA)
EINECS	Contact for details

Quality Control

Every batch of our 2-Cyanophenylboronic Acid Mida Ester is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage. Recommended storage temperature: 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.