Description

1-Phenylvinylboronic Acid Mida Ester is a specialized, protected boronic acid derivative that serves as a crucial synthetic intermediate in modern organic chemistry. Its core value lies in the enhanced stability and controlled reactivity provided by the MIDA (N-methyliminodiacetic acid) ligand, which prevents protodeboronation and enables complex, multi-step synthetic sequences. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require reliable, high-purity building blocks for Suzuki-Miyaura cross-coupling reactions and other catalytic transformations.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for creating complex biaryl and styrenyl structures via cross-coupling.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate vinyl-aryl motifs.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers and small molecules for OLEDs and OFETs, where precise molecular architecture is critical.
• Chemical Biology & Medicinal Chemistry: Serves as a versatile handle in the synthesis of chemical probes, PROTACs, and other tool compounds for target identification and validation.
• Academic & Process Chemistry: A valuable reagent for methodology development and scalable process optimization in academic and industrial R&D laboratories.

Basic Information

Product Name	1-Phenylvinylboronic Acid Mida Ester
CAS No.	1257651-50-5
Molecular Formula	C₁₃H₁₄BNO₄
Molecular Weight	259.07 g/mol
Synonyms	1-Phenylvinylboronic Acid MIDA Ester; N-Methyliminodiacetic Acid (1-Phenylvinyl)boronate; (1-Phenylvinyl)boronic Acid MIDA Ester; MIDA (1-Phenylvinyl)boronate; B-(1-Phenylvinyl)-N-methyliminodiacetic acid boronate; 1-Phenylvinyl MIDA Boronate; (1-Phenylethenyl)boronic Acid MIDA Ester; CAS 1257651-50-5
EINECS	Contact for details

Quality Control

Every batch of our 1-Phenylvinylboronic Acid Mida Ester is produced under strict quality management protocols. We employ advanced analytical techniques including NMR (¹H, ¹³C, ¹¹B), HPLC, and LC-MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. Our quality system is designed to meet the stringent requirements of cGMP for pharmaceutical intermediates and supports compliance with global regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) when possible to maintain long-term stability. Keep the container tightly sealed in a desiccator after opening.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.