Description

2,4-Dichloropyridine-3-Boronic Acid Pinacol Ester is a high-value, multi-functional organoboron building block essential for modern synthetic chemistry. Its core value lies in enabling efficient carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially in the development of kinase inhibitors and other heterocyclic drug candidates.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that require functionalized pyridine cores.
• Material Science: Serves as a monomer or cross-linking agent in the creation of organic electronic materials, such as those used in OLEDs and conductive polymers.
• Chemical Research & Development: A versatile reagent for constructing complex, multi-substituted pyridine derivatives in academic and industrial research laboratories.
• Ligand Synthesis: Precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Library Synthesis: Enables high-throughput parallel synthesis for drug discovery and lead optimization programs.

Basic Information

Item	Details
Product Name	2,4-Dichloropyridine-3-Boronic Acid Pinacol Ester
CAS No.	1257651-49-2
Molecular Formula	C11H12BCl2NO2
Molecular Weight	271.94 g/mol
Synonyms	2,4-Dichloro-3-pyridineboronic acid pinacol ester; (2,4-Dichloropyridin-3-yl)boronic acid pinacol ester; 3-Borono-2,4-dichloropyridine pinacol ester; 2,4-Dichloro-3-pyridinylboronic acid pinacol ester; 2,4-Dichloro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 1257651-49-2; Pinacol (2,4-dichloropyridin-3-yl)boronate
EINECS	Contact for details

Quality Control

Every batch of 2,4-Dichloropyridine-3-Boronic Acid Pinacol Ester is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. Our standard quality commitment includes comprehensive analysis via NMR, HPLC, and GC-MS. A detailed Certificate of Analysis (COA) confirming identity, purity, and impurity profile is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.