Description

Phenyl-[5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Thiophen-2-Ylmethylene]-Amine is a specialized organoboron building block featuring a boronic ester pinacol group and an imine functional group. This compound is of significant value in modern synthetic chemistry as a key intermediate for constructing complex molecular architectures via cross-coupling reactions. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of advanced materials, agrochemicals, and active pharmaceutical ingredients (APIs).

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a critical boronic ester reagent for the palladium-catalyzed formation of carbon-carbon bonds, essential for synthesizing conjugated systems.
• Pharmaceutical Intermediate: Used in the research and development of novel drug candidates, particularly those containing heterocyclic thiophene scaffolds.
• Organic Electronic Materials: A building block for synthesizing π-conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Agrochemical Synthesis: Employed in creating advanced active ingredients for crop protection products.
• Ligand and Catalyst Development: The imine functionality allows for its use in the preparation of novel chelating ligands for metal catalysis.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D exploring new synthetic methodologies and complex molecule construction.

Basic Information

Product Name	Phenyl-[5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Thiophen-2-Ylmethylene]-Amine
CAS No.	1257651-22-1
Molecular Formula	C₁₇H₂₀BNO₂S
Molecular Weight	313.22 g/mol
Synonyms	2-[[(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophen-2-yl)methylidene]amino]benzene; N-[(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophen-2-yl)methylene]aniline; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-thiophenecarboxaldehyde phenylimine; (E)-N-((5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)thiophen-2-yl)methylene)aniline; Thiophene boronic ester pinacol imine derivative
EINECS	Contact for details

Quality Control

Our Phenyl-[5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Thiophen-2-Ylmethylene]-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.