Description

2,2,6,6-Tetramethyl-1,2,3,6-Tetrahydro-4-Pyridineboronic Acid Pinacol Ester is a high-value, protected boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its primary value lies in its stability and reactivity, making it an essential reagent for constructing complex molecular architectures via cross-coupling reactions. This compound is particularly sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, especially those containing complex heterocyclic scaffolds.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, enabling the introduction of the tetramethylpiperidine moiety.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysts, and novel polymers where precise boron incorporation is required.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the development of chemical probes and inhibitors targeting specific enzymes or biological pathways.
• Catalyst Ligand Development: Serves as a starting material for synthesizing sophisticated nitrogen-boron containing ligands used in asymmetric catalysis.
• Academic & R&D Laboratories: A fundamental reagent for methodological development in organic synthesis and exploring new boron-mediated transformations.

Basic Information

Item	Detail
Product Name	2,2,6,6-Tetramethyl-1,2,3,6-Tetrahydro-4-Pyridineboronic Acid Pinacol Ester
CAS No.	1257651-11-8
Molecular Formula	C15H28BNO2
Molecular Weight	265.20 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,2,6,6-tetramethyl-1,2,3,6-tetrahydropyridine; 2,2,6,6-Tetramethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2,3,6-tetrahydropyridine; 1,2,3,6-Tetrahydro-2,2,6,6-tetramethyl-4-pyridineboronic acid pinacol ester; 4-BPin-THTMP; Tetramethylpiperidine-4-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Every batch of our 2,2,6,6-Tetramethyl-1,2,3,6-Tetrahydro-4-Pyridineboronic Acid Pinacol Ester is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive applications like pharmaceutical R&D. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal purity and reactivity. Recommended storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.