Description

4-[3-(1-Imidazolyl)Propylaminomethyl]Benzeneboronic Acid Pinacol Ester is a sophisticated boronic ester derivative designed for advanced organic synthesis and pharmaceutical research. This compound is a critical building block in modern medicinal chemistry, valued for its dual functionality as a protected boronic acid and a heterocyclic amine. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly for targeted drug delivery systems and enzyme inhibitor libraries.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for constructing biaryl and heterobiaryl structures in pharmaceutical intermediates.
• Protease Inhibitor Development: Serves as a core scaffold in the synthesis of potential inhibitors for enzymes like serine proteases.
• Bioconjugation and Linker Chemistry: Used to create cleavable linkers in antibody-drug conjugates (ADCs) and other targeted therapies.
• Materials Science Research: Employed in the synthesis of functionalized organic frameworks and polymers with specific binding properties.
• Chemical Biology Probes: Acts as a precursor for activity-based probes used to study enzyme function and localization.
• Library Synthesis for High-Throughput Screening: A valuable building block for generating diverse compound libraries in drug discovery campaigns.

Basic Information

Product Name	4-[3-(1-Imidazolyl)Propylaminomethyl]Benzeneboronic Acid Pinacol Ester
CAS No.	1257648-78-4
Molecular Formula	C19H28BN3O2
Molecular Weight	341.26 g/mol
Synonyms	4-[[3-(1H-Imidazol-1-yl)propylamino]methyl]benzeneboronic acid pinacol ester; 1H-Imidazole-1-propanamine, N-[(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methyl]-; 4-(3-Imidazol-1-yl-propylaminomethyl)-phenylboronic acid pinacol ester; N-[(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)methyl]-1H-imidazole-1-propanamine; Boronic acid, B-[4-[[[3-(1H-imidazol-1-yl)propyl]amino]methyl]phenyl]-, 1,1-dimethylethyl ester; CAS 1257648-78-4
EINECS	Contact for details

Quality Control

Our production of 4-[3-(1-Imidazolyl)Propylaminomethyl]Benzeneboronic Acid Pinacol Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research applications. All materials undergo comprehensive analytical characterization including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) providing purity, identity confirmation, and impurity profile is supplied with each batch to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent decomposition. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.