Description

6-Butyl-2-(4-Bromophenyl)-1,3,6,2-Dioxazaborocane CAS NO 1257642-68-4 is a specialized organoboron heterocyclic compound featuring a unique dioxazaborocane ring system. This compound is valued for its role as a versatile building block and catalyst precursor in advanced synthetic chemistry. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams for developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of boron-containing drug candidates, particularly for proteolysis-targeting chimeras (PROTACs) and enzyme inhibitors.
• Cross-Coupling Catalyst Ligand: Used in the preparation of ligands for palladium- or nickel-catalyzed cross-coupling reactions (e.g., Suzuki-Miyaura coupling).
• Material Science Research: Employed in the development of novel boron-based polymers, liquid crystals, or organic electronic materials.
• Agrochemical Synthesis: Acts as an intermediate for creating new generations of herbicides or fungicides with enhanced activity.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organoboron chemistry and heterocycle synthesis.

Basic Information

Product Name	6-Butyl-2-(4-Bromophenyl)-1,3,6,2-Dioxazaborocane
CAS No.	1257642-68-4
Molecular Formula	C₁₄H₂₁BBrNO₂
Molecular Weight	326.04 g/mol
Synonyms	2-(4-Bromophenyl)-6-butyl-1,3,6,2-dioxazaborocane; 6-Butyl-2-(4-bromophenyl)-1,3,6,2-dioxazaborinane; 4-Bromophenyl-6-butyl-dioxazaborocane; B-(4-Bromophenyl)-6-butyl-1,3,6,2-dioxazaborocane; Boron, [2-(4-bromophenyl)-1,3,6,2-dioxazaborocan-6-yl]-; (4-Bromophenyl)(6-butyl-1,3,6,2-dioxazaborocan-2-yl)boron
EINECS	Contact for details

Quality Control

Our 6-Butyl-2-(4-Bromophenyl)-1,3,6,2-Dioxazaborocane is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.