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3,5-Dichloro-4-Pyridineboronic Acid Pinacol Ester CAS NO 1257641-28-3


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CAS No.:1257641-28-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3,5-Dichloro-4-Pyridineboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for the development of new active ingredients and functional molecules.

Application

  • Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing substituted pyridine cores.
  • Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific halogenated pyridine structures.
  • Ligand and Catalyst Development: Employed in the creation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
  • Material Science Research: Acts as a building block for organic electronic materials, such as those used in OLEDs and semiconductors.
  • Chemical Biology Probes: Utilized in the synthesis of molecular probes and tags for studying biological systems.
  • Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name 3,5-Dichloro-4-Pyridineboronic Acid Pinacol Ester
CAS No. 1257641-28-3
Molecular Formula C11H14BCl2NO2
Molecular Weight 274.95 g/mol
Synonyms 4,6-Dichloro-3-pyridinylboronic acid pinacol ester; (4,6-Dichloropyridin-3-yl)boronic acid pinacol ester; 3,5-Dichloro-4-pyridinylboronic acid pinacol ester; 3,5-Dichloro-4-pyridylboronic acid pinacol ester; (3,5-Dichloro-4-pyridinyl)boronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,5-dichloropyridine; PINACOL 3,5-DICHLORO-4-PYRIDINEBORONATE
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Quality Control

Our 3,5-Dichloro-4-Pyridineboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable and can provide material to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when appropriate to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Assay (HPLC) ≥97.0%
Purity (HPLC, Area%) ≥98.0%
Water Content (KF) ≤0.5%
Residue on Ignition ≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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