Description

n-Ethyl-n-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is a high-value, advanced pharmaceutical intermediate featuring a pinacol boronate ester functional group. This compound is critical for enabling Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern synthetic chemistry for constructing complex molecules. It is primarily sought after by R&D and process chemistry teams in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), especially those containing biphenyl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Medicinal Chemistry: Employed in the discovery and optimization of drug candidates through efficient library synthesis and structure-activity relationship (SAR) studies.
• Catalyst & Ligand Development: Acts as a starting material for synthesizing novel ligands and catalysts used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis organizations (CSOs) serving the global life sciences industry.

Basic Information

Product Name	n-Ethyl-n-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine
CAS No.	1257554-16-7
Molecular Formula	C14H23BN2O2
Molecular Weight	262.16 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-ethyl-N-methylpyridin-2-amine; 2-Pyridinamine, N-ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-methyl-; N-Ethyl-N-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-ethyl-N-methyl-2-aminopyridine; N-Ethyl-N-methyl-5-(pinacolatoboryl)pyridin-2-amine; 5-(Pinacolatoboryl)-N-ethyl-N-methyl-2-aminopyridine; Boronic acid, [6-(ethylmethylamino)-3-pyridinyl]-, pinacol ester; CAS 1257554-16-7
EINECS	Contact for details

Quality Control

Every batch of n-Ethyl-n-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the exacting standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing purity (typically by HPLC/NMR), identity, and impurity profile is supplied with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition. Recommended long-term storage temperature is 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.