Description

3-Ethoxy-2-Methoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-purity, advanced pharmaceutical intermediate and a key building block in modern organic synthesis. This compound is valued for its role as a versatile boronic ester derivative, enabling critical carbon-carbon bond formation reactions. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients and complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A critical reagent for constructing biaryl and heterobiaryl structures in medicinal chemistry and material science.
• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with complex heterocyclic cores.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors, ligands for catalysts, and emissive layers for electronic devices.
• Chemical Biology & Probe Development: Useful for creating molecular probes and labeled compounds for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research labs for bespoke synthesis projects requiring specific boronate functionalities.

Basic Information

Item	Detail
Product Name	3-Ethoxy-2-Methoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1257554-14-5
Molecular Formula	C14H22BNO4
Molecular Weight	279.14 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-ethoxy-2-methoxypyridine; 3-Ethoxy-2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Methoxy-3-ethoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Pyridine, 3-ethoxy-2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 3-Ethoxy-2-methoxypyridine-5-boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 3-Ethoxy-2-Methoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.