Description

3-Isopropoxy-2-Methoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. This compound matters for its role as a key precursor in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic ester reagent for palladium-catalyzed carbon-carbon bond formation, essential for constructing biaryl and heterobiaryl structures.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its pyridine-boronate core.
• Material Science & OLED Development: Employed as a precursor for creating organic electronic materials, including charge-transport layers and emissive materials in OLED devices.
• Ligand Synthesis: Useful for the preparation of novel nitrogen-containing ligands for catalysis and coordination chemistry.
• Chemical Biology Probes: Acts as a handle for bioconjugation and the synthesis of molecular probes for target identification and validation.

Basic Information

Product Name	3-Isopropoxy-2-Methoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1257554-11-2
Molecular Formula	C15H24BNO4
Molecular Weight	293.17 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-isopropoxy-2-methoxypyridine; 2-Methoxy-3-isopropoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 3-Isopropoxy-2-methoxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; Pinacol 3-Isopropoxy-2-methoxypyridine-5-boronate; 5-Boronic acid, 3-(1-methylethoxy)-2-methoxypyridine, pinacol ester; Pyridine-5-boronic acid, 3-isopropoxy-2-methoxy-, pinacol ester
EINECS	Contact for details

Quality Control

Our 3-Isopropoxy-2-Methoxy-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. Certificates of Analysis (COA) with full analytical data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.