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2-Isopropoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine CAS NO 1257554-10-1


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CAS No.:1257554-10-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-Isopropoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients, as well as in materials science for creating advanced organic electronic components.

Application

  • Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in constructing pyridine-containing heterocycles prevalent in active pharmaceutical ingredients (APIs).
  • Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific biaryl linkages for optimal activity.
  • Material Science Research: Serves as a precursor for organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and other electronic materials where conjugated systems are crucial.
  • Ligand and Catalyst Development: Employed in the creation of novel ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
  • Chemical Biology & Probe Synthesis: Utilized to create molecular probes and labeled compounds for biological imaging and mechanism-of-action studies.
  • Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences and specialty chemicals markets.

Basic Information

Product Name 2-Isopropoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No. 1257554-10-1
Molecular Formula C14H22BNO3
Molecular Weight 263.14 g/mol
Synonyms 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-isopropoxypyridine; 2-Isopropoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-(Isopropoxy)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 4-Pinacolatoboryl-2-isopropoxypyridine; 2-Isopropoxy-4-pyridineboronic acid pinacol ester
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Quality Control

Our 2-Isopropoxy-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request, supporting your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening the container for use to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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