Description

2-Methyl-5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridin-3-Ylamine is a high-value pyridine-based boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its primary commercial value lies in its role as a versatile intermediate for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors, where it is used to develop new active ingredients and advanced functional molecules.

Application

• Pharmaceutical Intermediate: Key synthon for creating novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug discovery pipelines.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science & OLED Development: Acts as a precursor for synthesizing organic light-emitting diode (OLED) materials and other electronic chemicals requiring specific aryl-aryl linkages.
• Ligand & Catalyst Design: Employed in the development of novel bidentate ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology & Probe Development: Useful for labeling and modifying biomolecules, aiding in the creation of diagnostic tools and research probes.
• Polymer Chemistry: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers with tailored properties.

Basic Information

Product Name	2-Methyl-5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridin-3-Ylamine
CAS No.	1257554-08-7
Molecular Formula	C12H19BN2O2
Molecular Weight	234.11 g/mol
Synonyms	3-Amino-2-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 2-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-amine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-methylpyridin-3-amine; 2-Methyl-5-(pinacolatoboryl)pyridin-3-amine; 3-Amino-2-methyl-5-(pinacolatoboryl)pyridine; Pinacol 3-Amino-2-methylpyridine-5-boronate
EINECS	Contact for details

Quality Control

Every batch of 2-Methyl-5-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)Pyridin-3-Ylamine is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are supported by a detailed Certificate of Analysis (COA) that includes results from HPLC, NMR, and other relevant spectroscopic methods. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.