Description

2-(2-Hydroxy-3-(4-(3-Oxomorpholino)Phenylamino)Propyl)Isoindoline-1,3-Dione is a specialized organic compound featuring a complex molecular architecture that combines phthalimide and morpholinone pharmacophores. This compound matters as a high-value chemical intermediate or active pharmaceutical ingredient (API) building block for research and development in advanced therapeutic areas. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers focused on synthesizing novel drug candidates, particularly in oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting specific enzymes or receptors.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a potential linker or warhead component in the design of bifunctional molecules for targeted protein degradation.
• Kinase Inhibitor Research: Used in medicinal chemistry programs to develop and optimize inhibitors for various kinase targets implicated in cancer and inflammatory diseases.
• Chemical Biology Probe Synthesis: Employed to create tool compounds for studying biological pathways and protein function in academic and industrial research.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific advanced intermediates.

Basic Information

Product Name	2-(2-Hydroxy-3-(4-(3-Oxomorpholino)Phenylamino)Propyl)Isoindoline-1,3-Dione
CAS No.	1257527-98-2
Molecular Formula	C21H20N4O5
Molecular Weight	408.41 g/mol
Synonyms	N-[2-Hydroxy-3-[(4-(3-oxomorpholin-4-yl)phenyl)amino]propyl]phthalimide; 4-[4-[[2-Hydroxy-3-(1,3-dioxo-2-isoindolyl)propyl]amino]phenyl]-3-morpholinone; 2-[2-Hydroxy-3-({4-[3-oxomorpholin-4-yl]phenyl}amino)propyl]-1H-isoindole-1,3(2H)-dione; 2-(2-Hydroxy-3-{[4-(3-oxo-4-morpholinyl)phenyl]amino}propyl)-1H-isoindole-1,3(2H)-dione; 1257527-98-2; UNII-9S4I8K0A6T; 9S4I8K0A6T
EINECS	Contact for details

Quality Control

Our 2-(2-Hydroxy-3-(4-(3-Oxomorpholino)Phenylamino)Propyl)Isoindoline-1,3-Dione is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.