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2-(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Yl)Propan-2-Ol CAS NO 1257431-63-2


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CAS No.:1257431-63-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

2-(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Yl)Propan-2-Ol is a high-value pyridine-containing boronic ester derivative, serving as a critical building block in modern synthetic chemistry. Its core value lies in enabling the efficient construction of complex molecules through reliable cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and advanced materials.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
  • Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides with improved efficacy and selectivity.
  • Material Science: Serves as a monomer or functionalization agent in the creation of advanced polymers, ligands for catalysis, and organic electronic materials.
  • Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for constructing complex heterocyclic systems and exploring new chemical spaces.
  • Ligand Synthesis: Employed in the preparation of sophisticated ligands for transition metal catalysts used in asymmetric synthesis.
  • Diagnostic Probe Development: Utilized in the synthesis of molecular probes and sensors for biological imaging and detection applications.

Basic Information

Product Name 2-(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Yl)Propan-2-Ol
CAS No. 1257431-63-2
Molecular Formula C14H22BNO3
Molecular Weight 263.14 g/mol
Synonyms 2-[5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-pyridinyl]-2-propanol; 2-(5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)propan-2-ol; 3-(2-Hydroxypropan-2-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-(2-hydroxypropan-2-yl)pyridine; 2-(5-(Pinacolatoboryl)pyridin-3-yl)propan-2-ol; 3-(1-Hydroxy-1-methylethyl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
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Quality Control

Our 2-(5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-3-Yl)Propan-2-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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