Description

6-(3-Ethylureido)-4-(4-(Trifluoromethyl)-4,5-dihydrothiazol-2-yl)pyridin-3-ylboronic acid is a sophisticated boronic acid derivative and a high-value building block in modern synthetic chemistry. Its core value lies in enabling the precise construction of complex molecules, particularly through Suzuki-Miyaura cross-coupling reactions, which are fundamental to pharmaceutical and advanced materials research. This compound is essential for medicinal chemists and R&D teams in the pharmaceutical, agrochemical, and specialty chemical industries who are developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in oncology, CNS disorders, and anti-infective research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Suzuki-Miyaura Cross-Coupling: Serves as a critical boronic acid reagent for forming carbon-carbon bonds to construct complex biaryl and heterobiaryl structures.
• Material Science: Potential precursor for creating organic electronic materials, such as those used in OLEDs or organic semiconductors.
• Chemical Biology & Proteomics: Can be utilized in the development of chemical probes and activity-based protein profiling (ABPP) reagents.
• Library Synthesis: Enables the rapid generation of diverse compound libraries for high-throughput screening in drug discovery campaigns.

Basic Information

Product Name	6-(3-Ethylureido)-4-(4-(Trifluoromethyl)-4,5-dihydrothiazol-2-yl)pyridin-3-ylboronic Acid
CAS No.	1256913-17-3
Molecular Formula	C₁₂H₁₄BF₃N₄O₂S
Molecular Weight	346.14 g/mol
Synonyms	6-(3-Ethylureido)-4-(4-(trifluoromethyl)-4,5-dihydrothiazol-2-yl)pyridine-3-boronic acid; 3-Pyridineboronic acid, 6-[(ethylamino)carbonyl]amino]-4-(4,5-dihydro-4-(trifluoromethyl)-2-thiazolyl)-; 6-[(Ethylcarbamoyl)amino]-4-[4-(trifluoromethyl)-4,5-dihydro-1,3-thiazol-2-yl]pyridine-3-boronic acid; Boronic acid, B-[6-[[(ethylamino)carbonyl]amino]-4-[4,5-dihydro-4-(trifluoromethyl)-2-thiazolyl]-3-pyridinyl]-; CAS 1256913-17-3
EINECS	Contact for details

Quality Control

Our 6-(3-Ethylureido)-4-(4-(Trifluoromethyl)-4,5-dihydrothiazol-2-yl)pyridin-3-ylboronic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and reactivity. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.