Description

6-Bromo-5-(trifluoromethyl)nicotinaldehyde is a high-purity, multi-functional chemical building block featuring a reactive aldehyde group on a halogenated pyridine core. This compound is valued for its unique molecular architecture, which enables the synthesis of complex heterocyclic systems and functionalized intermediates. It is primarily sought by researchers and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the trifluoromethyl and bromo substituents for bioactivity.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science: Employed in the research and development of organic electronic materials, such as OLEDs and semiconductors, due to its electron-deficient aromatic system.
• Chemical Biology: Utilized as a probe or linker in bioconjugation chemistry and for the development of molecular imaging agents.
• Custom Synthesis: A versatile scaffold for contract research organizations (CROs) and custom synthesis houses to build complex, tailor-made molecules for client projects.

Basic Information

Product Name	6-Bromo-5-(trifluoromethyl)nicotinaldehyde
CAS No.	1256836-78-8
Molecular Formula	C7H3BrF3NO
Molecular Weight	253.01 g/mol
Synonyms	6-Bromo-5-(trifluoromethyl)pyridine-3-carbaldehyde; 3-Bromo-2-(trifluoromethyl)-5-pyridinecarboxaldehyde; 5-Bromo-6-(trifluoromethyl)nicotinaldehyde; 6-Bromo-5-trifluoromethylnicotinaldehyde; 6-Bromo-5-trifluoromethyl-3-pyridinecarboxaldehyde; 3-Pyridinecarboxaldehyde, 6-bromo-5-(trifluoromethyl)-; 6-Bromo-5-(trifluoromethyl)-3-pyridinecarbaldehyde
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-(trifluoromethyl)nicotinaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the material under an inert atmosphere for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.